C1S (heavy chain, Cleaved-Arg437) antibody detects endogenous levels of fragment of activated C1S resulting from cleavage adjacent to Arg437.
References:
McKinnon C.M., Eur. J. Biochem. 169:547-553(1987).
Tosi M., Biochemistry 26:8516-8524(1987).
Kusumoto H., Proc. Natl. Acad. Sci. U.S.A. 85:7307-7311(1988).
Western blot analysis of extracts from 293 cells treated with etoposide (25uM, 1hour) and HeLa cells treated with etoposide (25uM, 24hours), using C1S (heavy chain, Cleaved-Arg437) antibody.