• Catalog Number:

  E1A0230L-3

• Amount:

  100ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized peptide derived from human C1R.

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Reactivity:

  Human

• SwissProtNo:

  P00736

• Applications:

  WB: 1:500~1:1000 ELISA: 1:20000

• Other Names:

  Complement C1r subcomponent [Precursor], EC 3.4.21.41, Complement component 1, r subcomponent, Complement C1r subcomponent heavy chain, Complement C1r subcomponent light chain, C1R

• Specificity Sensitivity:

  C1R (light chain, Cleaved-Ile464) antibody detects endogenous levels of fragment of activated C1R resulting from cleavage adjacent to Ile464.

• References:

  Leytus S.P., Biochemistry 25:4855-4863(1986). Journet A., Biochem. J. 240:783-787(1986). Nakagawa M., Ann. Hum. Genet. 67:207-215(2003).

Western blot analysis of extracts from 293 cells treated with etoposide (25uM, 1hour) and A549 cells treated with etoposide (25uM, 24hours), using C1R (light chain, Cleaved-Ile464) antibody.