• Catalog Number:

  E1A0176L-2

• Amount:

  50ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized peptide derived from human CATD.

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Reactivity:

  Human

• SwissProtNo:

  P07339

• Applications:

  WB: 1:500~1:1000 ELISA: 1:40000

• Other Names:

  Cathepsin D [Precursor], EC 3.4.23.5, Cathepsin D light chain, Cathepsin D heavy chain, CTSD, CPSD

• Specificity Sensitivity:

  CATD (heavy chain, Cleaved-Leu169) antibody detects endogenous levels of fragment of activated CATD resulting from cleavage adjacent to Leu169

• References:

  Faust P.L., Proc. Natl. Acad. Sci. U.S.A. 82:4910-4914(1985). Westley B.R., Nucleic Acids Res. 15:3773-3786(1987). Redecker B., DNA Cell Biol. 10:423-431(1991).

Western blot analysis of extracts from 293 cells and NIH-3T3 cells treated with etoposide (25uM, 1hour), Jurkat cells and A549 cells treated with etoposide (25uM, 24hours), using CATD (heavy chain, Cleaved-Leu169) antibody.