• Catalog Number:

  E1A0134L-2

• Amount:

  50ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized peptide derived from human SPTA2.

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Reactivity:

  Human

• SwissProtNo:

  Q13813

• Applications:

  WB: 1:500~1:1000 ELISA: 1:10000

• Other Names:

  alpha-II spectrin; fodrin alpha; SPCN; spectrin alpha II; spectrin alpha, brain; spectrin, non-erythroid alpha; SPNA2; SPTA2

• Specificity Sensitivity:

  SPTA2 (Cleaved-Asp1185) antibody detects endogenous levels of fragment of activated SPTA2 resulting from cleavage adjacent to Asp1185.

• References:

  Moon R.T., J. Biol. Chem. 265:4427-4433(1990). Cianci C.D., Biochemistry 38:15721-15730(1999). Humphray S.J., Nature 429:369-374(2004).

Western blot analysis of extracts from HeLa cells and A549 cells, all treated with etoposide (25uM, 24hours), using SPTA2 (Cleaved-Asp1185) antibody.