• Catalog Number:

  E1A0119L-1

• Amount:

  30ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized peptide derived from human Notch 1 （VLLSRKRRC）.

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Reactivity:

  Human, Mouse, Rat

• SwissProtNo:

  P46531

• Applications:

  WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:5000

• Alter Name:

  NOTC1, NOTCH1, TAN1, hN1, neurogenic locus notch homolog protein 1, neurogenic locus notch homolog protein 1 precursor, notch (Drosophila) homolog 1 (translocation-associated), notch homolog 1, translocation-associated (Drosophila), translocation-associated notch protein TAN-1

• Specificity Sensitivity:

  Notch 1 (cleaved-Val1744) antibody detects endogenous levels of fragment of activated Notch 1 resulting from cleavage adjacent to Val1744.

• References:

  Kohshi Ohishi, Blood, May 2000; 95: 2847 - 2854. Eva Monsalve, J. Immunol., May 2006; 176: 5362 - 5373. R. Agarwal, Invest. Ophthalmol. Vis. Sci., May 2003; 44: 3340. Lin Shan, Am J Physiol Lung Cell Mol Physiol, Feb 2007; 292: L500 - L509.

• All Sites:

  Human: Val1744; Mouse: Val1744; Rat: Val2562

Cl-peptide - + Immunohistochemical analysis of paraffin-embedded human brain tissue using Notch 1 (cleaved-Val1744) antibody.

Western blot analysis of extracts from NIH/3T3 cells, treated with etoposide (25μM, 1hour), using Notch 1 (cleaved-Val1744) antibody.