• Catalog Number:

  E1A0116L-1

• Amount:

  30ul

• Form of Antibody:

  Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Storage/Stability:

  Store at -20℃/1 year

• class="eg_cn_title"Immunogen:

  The antiserum was produced against synthesized peptide derived from human Lamin A.

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Reactivity:

  Mouse, Rat

• SwissProtNo:

  P02545

• Applications:

  WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000

• Alter Name:

  70 kDa lamin, LAMA, LMN1, LMNA

• Specificity Sensitivity:

  Lamin A (cleaved-Asp230) antibody detects endogenous levels of fragment of activated Lamin A resulting from cleavage adjacent to Asp230.

• References:

  Revekka L. Boguslavsky, Hum. Mol. Genet., Feb 2006; 15: 653 - 663. Dan Constantinescu, Stem Cells, Jan 2006; 24: 177 - 185. Richard L. Frock, Genes & Dev., Feb 2006; 20: 486 - 500. Jan Lammerding, J. Biol. Chem., Sep 2006; 281: 25768 - 25780.

• All Sites:

  Human: Asp230; Mouse: Asp230; Rat: Asp229

Cl-peptide - + Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Lamin A (cleaved-Asp230) antibody.

Western blot analysis of extracts from HeLa cells, treated with etoposide (25μM, 1hour), using Lamin A (cleaved-Asp230) antibody.